Varicella Zoster Encephalitis

Inflammation of brain tissue caused by infection with the varicella-zoster virus (HERPESVIRUS 3, HUMAN). This condition is associated with immunocompromised states, including the ACQUIRED IMMUNODEFICIENCY SYNDROME. Pathologically, the virus tends to induce a vasculopathy and infect oligodendrocytes and ependymal cells, leading to CEREBRAL INFARCTION, multifocal regions of demyelination, and periventricular necrosis. Manifestations of varicella encephalitis usually occur 5-7 days after onset of HERPES ZOSTER and include HEADACHE; VOMITING; lethargy; focal neurologic deficits; FEVER; and COMA. (From Joynt, Clinical Neurology, 1996, Ch 26, pp29-32; Hum Pathol 1996 Sep;27(9):927-38)

Also Known As:

Encephalitis, Varicella; Zoster Encephalitis, Varicella; Encephalitis, Varicella Zoster; Encephalitis, Herpes Zoster; Encephalitis, VZ Virus; Herpes Zoster Meningoencephalitis; Varicella Encephalitides; Virus Encephalitis, VZ; Zoster Encephalitis, Herpes; Encephalitis, Human Herpesvirus 3; Herpes Zoster Encephalitis; Meningoencephalitis, Herpes Zoster; Varicella Encephalitis

Infections: 539155
- Virus Diseases: 42919
  - DNA Virus Infections: 145
    - Herpesviridae Infections: 836
      - Varicella Zoster Virus Infection: 252
        Varicella Zoster Encephalitis: 29
  - Central Nervous System Viral Diseases: 47
    - Viral Encephalitis: 480
      - Varicella Zoster Encephalitis: 29
- Central Nervous System Infections: 1428
  - Infectious Encephalitis: 58
    - Viral Encephalitis: 480
      - Varicella Zoster Encephalitis: 29
  - Central Nervous System Viral Diseases: 47
    - Viral Encephalitis: 480
      - Varicella Zoster Encephalitis: 29
Nervous System Diseases: 14737
- Neuroinflammatory Diseases: 19509
  - Encephalitis: 8670
    - Infectious Encephalitis: 58
      - Viral Encephalitis: 480
        Varicella Zoster Encephalitis: 29
- Central Nervous System Diseases: 4371
  - Brain Diseases: 16141
    - Encephalitis: 8670
      - Infectious Encephalitis: 58
        Viral Encephalitis: 480
        Varicella Zoster Encephalitis: 29
  - Central Nervous System Infections: 1428
    - Infectious Encephalitis: 58
      - Viral Encephalitis: 480
        Varicella Zoster Encephalitis: 29
    - Central Nervous System Viral Diseases: 47
      - Viral Encephalitis: 480
        Varicella Zoster Encephalitis: 29

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Disease

Drug/Important Bio-Agent (IBA)